Top 20 psych meds in 2005

The data is a little old but the numbers are still stagering.


Medication Used for… U.S. Prescriptions
1. Xanax Anxiety 34,230,000
2. Zoloft Depression, anxiety 26,976,000
3. Lexapro Depression, anxiety 24,788,000
4. Prozac Depression, anxiety 21,403,000
5. Ativan Anxiety, panic disorder 19,002,000
6. Effexor XR Depression, anxiety 17,179,000
7. Klonopin Anxiety 16,763,000
8. Elavil Depression, migraines 14,385,000
9. Valium Anxiety, panic disorder 12,093,000
10. Wellbutrin XL Depression 11,044,000
11. Celexa Depression, anxiety 9,266,000
12. Adderall XR Attention deficit disorder 8,653,000
13. Seroquel Antipsychotic, behavioral problems 8,420,000
14. Risperdal Antipsychotic 7,301,000
15. Strattera Attention deficit disorder 4,991,000
16. Cymbalta Depression, diabetes 4,938,000
17. Zyprexa Antipsychotic, behavioral problems 4,540,000
18. Depakote Bipolar, migraines 4,077,000
19. Buspar Sleep, anxiety 4,054,000
20. Paxil Depression, anxiety 3,609,000


Live imaging of adult rat brain rewiring itself:

Apparently there’s an online Journal of Visualized Experiments, JoVE, where you can find a myriad of snazzy videos like the one above.  Cool!

(via Neurophilosophy)

Jon Arbuckle

Who would have guessed that when you remove Garfield from the Garfield comic strips, the result is an even better comic about schizophrenia, bipolar disorder, and the empty desperation of modern life? Friends, meet Jon Arbuckle. Let’s laugh and learn with him on a journey deep into the tortured mind of an isolated young everyman as he fights a losing battle against loneliness in a quiet American suburb.

garfiled minus garfield

(via thisisjacq)


So Dr. Bazan seems to have figured out the mechanism of Omega-3 fatty acids’ neuroprotective quality.

Fish oil supplements contain two types of Omega-3 fatty acids, DHA and EPA. As it turns out DHA is the essential precursor for a protein Bazan coined NPD1 (neuroprotectin D1). The protein plays an important role in suppressing apoptosis (source).

Subsequently NPD1delays neurodegrenerative diseases like Parkinson’s (source) and curbs the acute immune response damage after stroke (source).

Dean Kamen

D6, a convention about all things digital, recently had Dean Kamen speak. Since, the blogosphere and twiterverse have both been buzzing.

Dean is the guy who invented the Segway and adapted that technology into the iBOT. He spoke at TED a while ago about his new project — now coined the “luke arm” — and, just recently, about its ‘completion’ at D6.

TED video

D6 Highlights via Wired

Youtube Video via Clusterflock

iBOT Commercial via Youtube

Activate Your Immune System…

by watching videos of your favorite actress!

The most recent post at The Neurocritic had me literally laughing out loud. I particularly enjoyed the footnote about the “scarry bunny furry wearing a gigantic clock“.

Music and Medicine

Seems music therapy is getting more attention these days. I wonder if Sacks’ latest book, Musicophilia, has anything to do with the press.

SciAm recently reported that depressed patients feel happier after listening to Beethoven.

Similarly, the NYT published a recent article about Claudius Conrad, an MD PhD surgeon at Harvard who’s investigating the biochemical nature of the Mozart-induced. Jonah Lehrer (The Frontal Cortex) comments.

The study itself was fairly simple. The researchers fitted 10 postsurgical intensive-care patients with headphones, and in the hour just after the patients’ sedation was lifted, 5 were treated to gentle Mozart piano music while 5 heard nothing.

The patients listening to music showed several responses that Dr. Conrad expected, based on other studies: reduced blood pressure and heart rate, less need for pain medication and a 20 percent drop in two important stress hormones, epinephrine and interleukin-6, or IL-6. Amid these expected responses was the study’s new finding: a 50 percent jump in pituitary growth hormone.

Interesting stuff, though, Dr. Conrad seems a little full of himself:

Thus, future studies are necessary to investigate how this beneficial effect of music can be further integrated clinically, both for patient and for physician.[13,14]

That’s my opinion. I am Dr. Claudius Conrad, Senior Surgical Resident, Harvard Medical School, Massachusetts General Hospital.